Angst J
Zurich University Psychiatric Hospital, Switzerland.
J Affect Disord. 1998 Sep;50(2-3):143-51. doi: 10.1016/s0165-0327(98)00142-6.
The literature on the lifetime prevalence of the bipolar spectrum suggests rates of 3-6.5%. The Zurich cohort study identified a prevalence rate up to age 35 of 5.5% of DSM-IV hypomania/mania and a further 2.8% for brief hypomania (recurrent and lasting 1-3 days). The validity of DSM-IV hypomania and brief hypomania was demonstrated by a family history of mood disorders, a history of suicide attempts and treatment for depression. Comorbidity with anxiety disorders and substance abuse was found equally in both subtypes of hypomania. The study suggests that recurrent brief hypomania belongs to the bipolar spectrum. The findings should be verified on larger national cohorts in other epidemiological and clinical studies.
关于双相谱系终生患病率的文献表明患病率为3 - 6.5%。苏黎世队列研究确定，到35岁时，DSM - IV轻躁狂/躁狂的患病率为5.5%，短暂轻躁狂（反复出现且持续1 - 3天）的患病率为2.8%。情绪障碍家族史、自杀未遂史和抑郁症治疗史证明了DSM - IV轻躁狂和短暂轻躁狂的有效性。在轻躁狂的两种亚型中，焦虑症和物质滥用的共病情况相当。该研究表明，反复出现的短暂轻躁狂属于双相谱系。这些发现应在其他流行病学和临床研究中的更大规模国家队列中得到验证。
