骨髓瘤中放射性药物分布改变：骨显像剂出现在心脏，而心脏显像剂出现在骨骼。

Altered radiopharmaceutical distribution in myeloma: bone tracer in the heart and heart tracer in the bone.

作者信息

Gupta A K, Meyer P, Gross M D, Fig L M, Shapiro B

机构信息

Department of Radiology, University of Michigan Medical Center, Ann Arbor, USA.

出版信息

Clin Nucl Med. 1998 Dec;23(12):820-3. doi: 10.1097/00003072-199812000-00006.

DOI:10.1097/00003072-199812000-00006

PMID:9858293

Abstract

Tissue deposits of amyloid may lead to various clinical symptoms and signs, depending on the site of deposition. In addition, a specific subtype of amyloidosis, AL protein type, is associated with multiple myeloma. Two cases representing contrasting examples of altered radiopharmaceutical biodistribution in myeloma and amyloidosis are presented and discussed, with a bone tracer depicting the heart and a heart tracer depicting the bones.

摘要

淀粉样蛋白的组织沉积可能会导致各种临床症状和体征，这取决于沉积部位。此外，一种特定亚型的淀粉样变性，即AL蛋白型，与多发性骨髓瘤有关。本文介绍并讨论了两个病例，它们代表了骨髓瘤和淀粉样变性中放射性药物生物分布改变的对比实例，其中一个骨显像剂显示心脏，一个心脏显像剂显示骨骼。