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[寄生于牛的吸虫的异柠檬酸脱氢酶及其使用驱虫制剂抑制它们的可行性]

[Isocitrate dehydrogenases of trematodes parasitizing cattle and the feasibility of inhibiting them using anthelmintic preparations].

作者信息

Burenina E A

出版信息

Parazitologiia. 1998 Sep-Oct;32(5):450-6.

PMID:9859128
Abstract

Activities and properties of NADF-dependent isocitrate dehydrogenases in cytosol and mitochondrial fractions from trematodes Eurytrema pancreaticum and Calicophoron ijimai were examined. Cytosol and mitochondrial enzymes were activated by ions Mn2+ and Mg2+ and inhibited by ions of heavy metals and p-chloromercuribenzoate. The effect of anthelmintic preparations on activity of enzymes was investigated.

摘要

对胰阔盘吸虫和饭岛杯殖吸虫胞质和线粒体部分中依赖NADF的异柠檬酸脱氢酶的活性及性质进行了研究。胞质和线粒体酶被Mn2+和Mg2+离子激活,并被重金属离子和对氯汞苯甲酸抑制。研究了驱虫制剂对酶活性的影响。

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