Krüger S, McVey G, Kennedy S H
University of Bochum, Westfalisches Zentrum Psychiatrie, Germany.
J Psychosom Res. 1998 Dec;45(6):533-47. doi: 10.1016/s0022-3999(98)00026-9.
The present study is a retrospective comparison of anorexic patients of the restricting subtype (AN) with those of the bulimic subtype (AN+BN) over three consecutive 5-year time periods. Subjects consisted of 806 female out-patients diagnosed as either AN or AN+BN between 1978 and 1994 during an assessment of their eating problem at the University of Toronto Programme for Eating Disorders in Toronto, Canada. During each time period an increasing proportion of subjects was diagnosed with AN+BN than with AN. Subjects with AN+BN reported a longer duration of illness prior to being assessed. Over time, subjects in both groups appeared to weigh more, and were less likely to report amenorrhea. Subjects from both groups reported higher frequencies of purging behavior, impulsive behaviors, and associated affective symptoms in the later time periods. Over time, the differences between the two subgroups of patients became less distinct. The results indicate changes in the clinical profile of patients with anorexia nervosa seen at the Toronto Programme for Eating Disorders over the past 16 years. The implications of these changes are explored.
本研究是对连续三个5年时间段内限制型厌食症患者(AN)与暴食型厌食症患者(AN+BN)进行的回顾性比较。研究对象包括1978年至1994年间在加拿大多伦多大学饮食失调项目中接受饮食问题评估时被诊断为AN或AN+BN的806名女性门诊患者。在每个时间段内,被诊断为AN+BN的患者比例都高于AN患者。AN+BN患者在接受评估前报告的病程更长。随着时间的推移,两组患者的体重似乎都有所增加,且闭经的可能性降低。两组患者在后期报告的清除行为、冲动行为及相关情感症状的频率更高。随着时间的推移,这两个亚组患者之间的差异变得不那么明显。结果表明,在过去16年里,多伦多饮食失调项目中神经性厌食症患者的临床特征发生了变化。本文探讨了这些变化的影响。