Thurmon J C, Kumar A, Cawley A J
Aust Vet J. 1975 Oct;51(10):484-7. doi: 10.1111/j.1751-0813.1975.tb02387.x.
pH, PaCO2, PaO2, standard bicarbonate, base excess and reduced pH were measured in sheep before and at regular intervals after administration of ketamine with and without atropine and acepromazine premedication. A decrease in pH and PaO2 and a rise in PaCO2 was observed 15 minutes after administration of ketamine. Administration of atropine with and without acepromazine had no significant effect on pH, PaCO2 and PaO2. The values for standard bicarbonate, base excess and reduced pH were not significantly affected. This indicates that minor changes observed in pH, PaCO2 after ketamine administration are compensated for by the healthy animal's blood buffer system.
在绵羊身上，于给予氯胺酮之前以及在给予氯胺酮且有或没有阿托品和乙酰丙嗪预处理的情况下，按固定间隔测量pH值、动脉血二氧化碳分压（PaCO2）、动脉血氧分压（PaO2）、标准碳酸氢盐、碱剩余和校正pH值。给予氯胺酮15分钟后，观察到pH值和PaO2下降以及PaCO2上升。无论有无乙酰丙嗪，给予阿托品对pH值、PaCO2和PaO2均无显著影响。标准碳酸氢盐、碱剩余和校正pH值未受到显著影响。这表明给予氯胺酮后在pH值、PaCO2方面观察到的微小变化可由健康动物的血液缓冲系统代偿。
