盐酸氯胺酮/乙酰丙嗪组合对健康猫的心肺影响。
Cardiopulmonary effects of a ketamine hydrochloride/acepromazine combination in healthy cats.
作者信息
Ingwersen W, Allen D G, Dyson D H, Pascoe P J, O'Grady M R
机构信息
Department of Clinical Studies, Ontario Veterinary College, University of Guelph.
出版信息
Can J Vet Res. 1988 Jan;52(1):1-4.
The effect of a ketamine hydrochloride/acepromazine combination on the cardiopulmonary function of 11 healthy cats was studied. Test parameters included cardiac output, measured by thermodilution, heart rate, respiratory rate, arterial blood pressure (systolic, diastolic and mean) and arterial blood gas analysis. Values for systemic vascular resistance, cardiac index and stroke volume were calculated. The cardiac output, cardiac index, stroke volume, arterial blood pressure and arterial blood pH decreased significantly (p less than 0.006). The arterial CO2 increased significantly (p less than 0.006). All changes occurred during the five to 45 minute postinduction time period. The heart rate, respiratory rate, arterial O2 and systemic vascular resistance were not significantly altered. The anesthetic regime maintained an adequate plane of surgical anesthesia for 30-45 minutes.
研究了盐酸氯胺酮/乙酰丙嗪组合对11只健康猫心肺功能的影响。测试参数包括通过热稀释法测量的心输出量、心率、呼吸频率、动脉血压（收缩压、舒张压和平均压）以及动脉血气分析。计算了全身血管阻力、心脏指数和每搏输出量的值。心输出量、心脏指数、每搏输出量、动脉血压和动脉血pH值显著降低（p小于0.006）。动脉二氧化碳显著增加（p小于0.006）。所有变化均发生在诱导后5至45分钟的时间段内。心率、呼吸频率、动脉血氧和全身血管阻力无显著改变。麻醉方案维持了30 - 45分钟的足够外科麻醉平面。
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