Yagishita A, Arai N, Tamagawa K, Oda M
Department of Neuroradiology, Tokyo Metropolitan Neurological Hospital, Japan.
Neuroradiology. 1998 Nov;40(11):734-8. doi: 10.1007/s002340050674.
We reviewed the MRI of 17 patients with hemimegalencephaly to investigate abnormal myelination in this condition. On images of seven patients aged 18 months or less, the white matter on the affected side suggested advanced myelination for the age. On T1-weighted images of three patients aged 1 month, the anterior limb of the internal capsule in the affected hemisphere was myelinated, and T1 shortening was not clearly seen in the pre- and postcentral gyri. The cortical grey matter and subcortical white matter was isointense in two patients. Images of two patients aged 4 to 5 months and of five patients aged 8-18 months showed myelination that extended more peripherally in the white matter of the affected hemisphere.
我们回顾了17例半侧巨脑回患者的MRI，以研究这种情况下的髓鞘形成异常。在7例18个月及以下患者的图像上，患侧白质显示出与年龄不符的髓鞘形成提前。在3例1个月大患者的T1加权图像上，患侧半球内囊前肢有髓鞘形成，中央前回和中央后回未见明显T1缩短。2例患者的皮质灰质和皮质下白质呈等信号。2例4至5个月大患者及5例8至18个月大患者的图像显示，患侧半球白质的髓鞘形成向更外周延伸。
