Senault B
Psychopharmacologia. 1976 Mar 16;46(2):167-8. doi: 10.1007/BF00421387.
In rats characterized by aggressive behaviour induced by apomorphine, only amantadine in doses of 10 mg/kg i.v. and 50 mg/kg i.p. induces a very slight aggressive effect, but in doses of 30 and 50 mg/kg i.p. it inhibits the aggressive behaviour induced by 1 mg/kg apomorphine. The effect is dose-related and it is more pronounced when amantadine (50 mg/kg i.p.) is injected 30 min rather than 1 h before apomorphine.
在以阿扑吗啡诱导攻击行为为特征的大鼠中，只有静脉注射10mg/kg和腹腔注射50mg/kg剂量的金刚烷胺会产生非常轻微的攻击作用，但腹腔注射30mg/kg和50mg/kg剂量时，它会抑制1mg/kg阿扑吗啡诱导的攻击行为。该作用与剂量相关，且当在阿扑吗啡注射前30分钟而非1小时注射金刚烷胺（腹腔注射50mg/kg）时，这种作用更明显。
