Chong V F, Fan Y F, Mukherji S K
Department of Diagnostic Radiology, Singapore General Hospital, Singapore.
Semin Ultrasound CT MR. 1998 Dec;19(6):449-62. doi: 10.1016/s0887-2171(98)90048-8.
Nasopharyngeal carcinoma (NPC) is an intriguing disease that shows a distinct geographical distribution with well-defined, high-risk ethnic groups. This neoplasm exhibits strong associations with the Epstein-Barr virus, dietary and genetic factors. Radiation therapy is the mainstay of treatment and imaging plays a central role in tumor mapping and radiation therapy planning. NPC provides an excellent model for the study of normal and pathological anatomy of the skull base. It also provides an excellent model in the study of consequences of radiation therapy.
鼻咽癌(NPC)是一种引人关注的疾病,其呈现出明确的地理分布以及特定的高危族群。这种肿瘤与爱泼斯坦-巴尔病毒、饮食和遗传因素密切相关。放射治疗是主要的治疗手段,而影像学在肿瘤定位和放射治疗计划中起着核心作用。鼻咽癌为研究颅底的正常和病理解剖学提供了一个极佳的模型。它在放射治疗后果的研究中也提供了一个极佳的模型。