Van Trappen P, Serreyn R, Elewaut A E, Cocquyt V, Van Belle S
Department of Gynaecological Oncology, University Hospital Ghent, Belgium.
Ann Oncol. 1998 Nov;9(11):1243-5. doi: 10.1023/a:1008287007819.
Breast cancer is the second commonest primary tumour responsible for gastrointestinal metastases after malignant melanoma. The real incidence of gastrointestinal metastases in breast cancer patients is probably underestimated owing to the non-specific presenting symptoms and death of patients caused by other more obvious metastases. The predominant histological subtype of gastrointestinal metastases of breast cancer is invasive lobular carcinoma and the median interval from diagnosis of primary breast cancer to gastrointestinal metastases is five years. We report two cases of disseminated breast cancer with gastrointestinal involvement with a rather long survival.
乳腺癌是继恶性黑色素瘤之后导致胃肠道转移的第二常见原发性肿瘤。由于非特异性的临床表现以及患者因其他更明显转移灶导致的死亡,乳腺癌患者胃肠道转移的实际发生率可能被低估。乳腺癌胃肠道转移的主要组织学亚型是浸润性小叶癌,从原发性乳腺癌诊断到胃肠道转移的中位间隔时间为五年。我们报告两例伴有胃肠道受累的播散性乳腺癌病例,患者生存期较长。