[17β-雌二醇与组蛋白的相互作用。激素对部分重构的肌组蛋白的影响]
[Interaction of 17beta-estradiol with histones. Effect of the hormone on partially reconstructed mucleohistones].
作者信息
Maĭskiĭ A I, Ogurtsov S I, Portugalov S N
出版信息
Biull Eksp Biol Med. 1976 Jun;81(6):666-8.
Binding of 17beta-estradiol with histones of calf thymus and the influence of the hormone on heart denaturing of partially reconstructed nucleohistones were investigated. By the degree of the hormone binding histone fractions could be arranged in the following order: F2a greater than F3 greater than F1 greater than or equal F2b. Addition of 17beta-estradiol gave rise to increase of the first and a corresponding decrease of the second melting phase of partially reconstructed nucleohistones F2a, F3 and F2b. Addition of the hormone to the partially reconstructed nucleohistone F1 gave rise to the opposite changes in the heat denaturing profile.
研究了17β-雌二醇与小牛胸腺组蛋白的结合以及该激素对部分重构核组蛋白热变性的影响。根据激素结合程度，组蛋白组分可按以下顺序排列：F2a＞F3＞F1≥F2b。添加17β-雌二醇会导致部分重构核组蛋白F2a、F3和F2b的第一个熔解相增加，第二个熔解相相应减少。向部分重构核组蛋白F1中添加该激素会使热变性曲线发生相反的变化。
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