Kihara M, Nakashima H, Takahashi M, Kawamura Y
Department of Neurology, Kinki University School of Medicine, Osaka-Sayama, Osaka, Japan.
J Auton Nerv Syst. 1998 Nov 10;73(2-3):186-9. doi: 10.1016/s0165-1838(98)00139-8.
To investigate the usefulness of the Composite Autonomic Scoring Scale (CASS) as an indication for autonomic dysfunction with Guillain-Barré syndrome, we quantitated autonomic deficits on follow-up using CASS in a patient with Guillain-Barré syndrome who did not have any autonomic symptoms and had good clinical recovery. Using the CASS we found the patient to have mild autonomic dysfunction but with a period of recovery. The scale showed that adrenergic deficits improved quickly, sudomotor deficits recovered moderately and cardiovagal deficits did not improve. These results suggested that the patient with Guillain-Barré syndrome might have dysautonomia although she did not have any autonomic symptoms. Results also suggest that there might be difference on the degree of improvement among adrenergic, sudomotor and cardiovagal deficits in Guillain-Barré syndrome. The CASS may be a sensitive tool for the detection of autonomic dysfunction in Guillain-Barre syndrome.
为了研究复合自主神经评分量表(CASS)作为吉兰-巴雷综合征自主神经功能障碍指标的实用性,我们在一名没有任何自主神经症状且临床恢复良好的吉兰-巴雷综合征患者的随访中,使用CASS对自主神经功能缺损进行了量化。通过CASS,我们发现该患者存在轻度自主神经功能障碍,但有一段恢复时期。该量表显示,肾上腺素能功能缺损改善迅速,汗腺运动功能缺损恢复中等,而心血管迷走神经功能缺损未改善。这些结果表明,该吉兰-巴雷综合征患者可能存在自主神经功能异常,尽管她没有任何自主神经症状。结果还表明,吉兰-巴雷综合征患者的肾上腺素能、汗腺运动和心血管迷走神经功能缺损在改善程度上可能存在差异。CASS可能是检测吉兰-巴雷综合征自主神经功能障碍的一种敏感工具。