Gasche C, Moser G, Turetschek K, Schober E, Moeschl P, Oberhuber G
Clinic of Internal Medicine IV, Department of Gastroenterology and Hepatology, Vienna, Austria.
Gut. 1999 Jan;44(1):112-7. doi: 10.1136/gut.44.1.112.
The course of Crohn's disease is characterised by the occurrence of intestinal complications such as strictures, intra-abdominal fistulas, or abscesses. Standard diagnostic procedures may fail to show these complications, in particular fistulas.
To test the value of transabdominal bowel sonography (T) for the detection of intestinal complications in Crohn's disease.
T was prospectively performed in 213 patients with Crohn's disease in a university based inflammatory bowel disease referral centre. Thirty three underwent resective bowel surgery and were included in this study. The accuracy of T to detect strictures, intra-abdominal fistulas, or abscesses was compared with surgical and pathological findings.
T was able to identify strictures in 22/22 patients and to exclude it in 10/11 patients (100% sensitivity, 91% specificity). Fistulas were correctly identified in 20/23 patients and excluded in 9/10 patients (87% sensitivity, 90% specificity). Intra-abdominal abscesses were correctly detected in 9/9 patients and excluded in 22/24 patients (100% sensitivity, 92% specificity).
In experienced hands T is an accurate method for the detection of intestinal complications in Crohn's disease. T is thus recommended as a primary investigative method for evaluation of severe Crohn's disease.
克罗恩病的病程特点是出现肠道并发症,如狭窄、腹腔内瘘或脓肿。标准诊断程序可能无法显示这些并发症,尤其是瘘。
检验经腹肠道超声检查(T)在检测克罗恩病肠道并发症中的价值。
在一家大学附属医院的炎症性肠病转诊中心,对213例克罗恩病患者前瞻性地进行了T检查。其中33例接受了肠切除手术并纳入本研究。将T检测狭窄、腹腔内瘘或脓肿的准确性与手术和病理结果进行比较。
T能够在22/22例患者中识别出狭窄,并在10/11例患者中排除狭窄(敏感性100%,特异性91%)。在20/23例患者中正确识别出瘘,在9/10例患者中排除瘘(敏感性87%,特异性90%)。在9/9例患者中正确检测出腹腔内脓肿,在22/24例患者中排除脓肿(敏感性100%,特异性92%)。
在经验丰富的医生手中,T是检测克罗恩病肠道并发症的准确方法。因此,建议将T作为评估重度克罗恩病的主要检查方法。