Zhu M, Gong Y, Ge G
Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing.
Zhonghua Yu Fang Yi Xue Za Zhi. 1997 Nov;31(6):325-9.
C57/BL6J mice were inoculated with Lewis lung cancer cells as an experimental model to study the effects of green tea on cancer prevention, inhibition of tumor growth and immune regulation in mice with tumor. Results showed that weight of thymus in C57/BL6J mice and its index declined, proportion of positive CD4 subgroup of T lymphocyte and ratio of CD4+, to CD8+ reduced, baseline chemilumi-nescence decreased in peripheral white blood cells, yeast zymosan stimulated chemiluminescence increased, and number of immunoglobulin M formation cells decreased. It indicated that green tea had obvious inhibition in Lewis lung cancer and protective effects, to various extent, on adverse changes of above indices.
将C57/BL6J小鼠接种Lewis肺癌细胞作为实验模型，以研究绿茶对荷瘤小鼠癌症预防、肿瘤生长抑制及免疫调节的影响。结果显示，C57/BL6J小鼠胸腺重量及其指数下降，T淋巴细胞CD4阳性亚群比例及CD4⁺与CD8⁺比值降低，外周血白细胞基础化学发光降低，酵母聚糖刺激化学发光增加，免疫球蛋白M形成细胞数量减少。这表明绿茶对Lewis肺癌有明显抑制作用，并对上述指标的不良变化有不同程度的保护作用。
