Kunst P W, Vonk Noordegraaf A, Hoekstra O S, Postmus P E, de Vries P M
Department of Pulmonary Medicine, Academic Hospital Vrije Universiteit, Amsterdam, The Netherlands.
Physiol Meas. 1998 Nov;19(4):481-90. doi: 10.1088/0967-3334/19/4/003.
Electrical impedance tomography (EIT) is a technique that makes it possible to measure ventilation and pulmonary perfusion in a volume that approximates to a 2D plane. The possibility of using EIT for measuring the left-right division of ventilation and perfusion was compared with that of radionuclide imaging. Following routine ventilation (81mKr) and perfusion scanning (99mTc-MAA), EIT measurements were performed at the third and the sixth intercostal level in 14 patients with lung cancer. A correlation (r = 0.98, p < 0.005) between the left-right division for the ventilation measured with EIT and that with 81mKr was found. For the left-right division of pulmonary perfusion a correlation of 0.95 (p < 0.005) was found between the two methods. The reliability coefficient (RC) was calculated for estimating the left-right division with EIT. The RC for the ventilation measurements was 94% and 96% for the perfusion measurements. The correlation analysis for reproducibility of the EIT measurements was 0.95 (p < 0.001) for the ventilation and 0.93 (p < 0.001) for the perfusion measurements. In conclusion, EIT can be regarded as a promising technique to estimate the left-right division of pulmonary perfusion and ventilation.
电阻抗断层成像（EIT）是一种能够在近似二维平面的容积内测量通气和肺灌注的技术。将使用EIT测量通气和灌注左右分布的可能性与放射性核素成像进行了比较。在14例肺癌患者中，在常规通气（81mKr）和灌注扫描（99mTc-MAA）后，于第三和第六肋间水平进行EIT测量。发现EIT测量的通气左右分布与81mKr测量的通气左右分布之间存在相关性（r = 0.98，p < 0.005）。两种方法在肺灌注左右分布方面的相关性为0.95（p < 0.005）。计算了用EIT估计左右分布的可靠性系数（RC）。通气测量的RC为94%，灌注测量的RC为96%。EIT测量重复性的相关性分析显示，通气测量为0.95（p < 0.001），灌注测量为0.93（p < 0.001）。总之，EIT可被视为一种有前景的技术，用于估计肺灌注和通气的左右分布。
