el Mezni F, Mrad K, el Mezni-Benzarti A, Zermani R, Ben Abdeladhim A, Ben Jilani S
Service d'Anatomie Pathologique, Hôpital Charles-Nicolle, Tunis, Tunisie.
Ann Pathol. 1998 Nov;18(5):422-4.
Histiocytic necrotizing lymphadenitis, also known as Kikuchi-Fujimoto disease is a rare self-limited condition of young adults usually misdiagnosed as malignant hematologic disease. The diagnosis depends on microscopic findings. Two histologic types are classically described, proliferative and necrotic types. This is a case report of 17 year-old girl who presented cervical lymphadenopathy. The first lymph node biopsy was in favor of malignant lymphoma. The second lymph node biopsy, done one month later, showed typical histiocytic necrotizing lymphadenitis. To our knowledge, this is the first time that the two forms of this disease are described in the same patient.
组织细胞坏死性淋巴结炎，又称菊池-藤本病，是一种罕见的自限性疾病，好发于年轻人，常被误诊为恶性血液病。诊断依赖于显微镜下表现。经典描述有两种组织学类型，即增生型和坏死型。本文报告一例17岁女性，表现为颈部淋巴结病。首次淋巴结活检结果支持恶性淋巴瘤。一个月后进行的第二次淋巴结活检显示为典型的组织细胞坏死性淋巴结炎。据我们所知，这是首次在同一患者身上描述该病的两种形式。
