Tobías Garcés A, Sunyer Deu J, Castellsagué Piqué J, Sáez Zafra M, Antó Boqué J M
Unitat de Recerca Respiratòria i Ambiental, Universitat Autònoma de Barcelona.
Gac Sanit. 1998 Sep-Oct;12(5):223-30. doi: 10.1016/s0213-9111(98)76476-3.
Air pollution has been associated with increased mortality according to studies carried out in the US. The APHEA project (Air Pollution on Health: a European Approach) analyzes the short-term effects in 15 european cities. We evaluated the acute relation between air pollution, mortality, and hospital emergency-room visits in Barcelona, one of the cities participating in the APHEA project.
Daily variations in total mortality, cardiovascular mortality, respiratory mortality, and emergency-room visits for chronic obstructive pulmonary disease (COPD), and asthma were studied in relation to daily variations in air pollution levels in 1985-1991. Poisson regression was done and temperature, relative humidity, and epidemics of asthma and flu were controlled. Temporal trends and auto-regressive terms were examined.
A reduction of about 50 micrograms/m3 in particles and sulfur dioxide was accompanied by a reduction of about 4% and 6% (p < 0.05), respectively, in daily deaths from respiratory and cardiovascular causes and emergency-room visits for COPD. Oxidant pollutants (nitrogen dioxide and ozone) were related positively with cardiovascular mortality and emergency visits for COPD and asthma. The role of ozone was notable, with a reduction in ozone levels of 50 micrograms/m3 originating a 4% reduction in emergency-room visits for COPD and asthma (p < 0.05).
Current levels of air pollutants had an epidemiologically measurable impact on mortality and emergency-room visits in Barcelona. These results were consistent with the findings of similar studies in other european and american cities and with previous studies of emergency-room admissions in Barcelona. These studies suggest the possible toxicity of air pollution.
根据美国开展的研究,空气污染与死亡率上升有关。APHEA项目(空气污染对健康的影响:欧洲的方法)分析了15个欧洲城市的短期影响。我们评估了参与APHEA项目的城市之一巴塞罗那空气污染、死亡率和医院急诊就诊之间的急性关系。
研究了1985 - 1991年期间总死亡率、心血管死亡率、呼吸死亡率以及慢性阻塞性肺疾病(COPD)和哮喘急诊就诊的每日变化与空气污染水平每日变化的关系。进行了泊松回归,并控制了温度、相对湿度以及哮喘和流感的流行情况。检查了时间趋势和自回归项。
颗粒物和二氧化硫浓度每降低约50微克/立方米,呼吸和心血管原因导致的每日死亡以及COPD急诊就诊分别减少约4%和6%(p < 0.05)。氧化剂污染物(二氧化氮和臭氧)与心血管死亡率以及COPD和哮喘急诊就诊呈正相关。臭氧的作用显著,臭氧水平降低50微克/立方米会使COPD和哮喘急诊就诊减少4%(p < 0.05)。
当前的空气污染物水平在巴塞罗那对死亡率和急诊就诊产生了可在流行病学上测量的影响。这些结果与其他欧美城市类似研究的结果以及巴塞罗那之前关于急诊入院的研究结果一致。这些研究表明空气污染可能具有毒性。