Kim Y S, Maslinski W, Zheng X X, Schachter A D, Strom T B
Harvard Medical School, Division of Immunology Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
Transplant Proc. 1998 Dec;30(8):4031-6. doi: 10.1016/s0041-1345(98)01330-x.
Advances in the understanding of genetic engineering, protein expression, and Ig function have come together to allow for the rapid synthesis and production of a novel generation of potent immunomodulating reagents. Selective approaches that allow the isolation of desired specificities will be elucidated through meticulous engineering techniques. This, in turn, may eventually result in the fulfillment of the tremendous potential of engineered proteins for therapeutic and diagnostic applications.
在基因工程、蛋白质表达和免疫球蛋白功能理解方面的进展共同促成了新一代强效免疫调节试剂的快速合成与生产。通过精细的工程技术将阐明能够分离所需特异性的选择性方法。反过来，这最终可能会实现工程蛋白在治疗和诊断应用方面的巨大潜力。
