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跨突触小脑模型中神经元脱失率

Rate of neuronal fallout in a transsynaptic cerebellar model.

作者信息

Triarhou L C

机构信息

Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis 46202-5120, USA.

出版信息

Brain Res Bull. 1998 Oct;47(3):219-22. doi: 10.1016/s0361-9230(98)00076-8.

DOI:10.1016/s0361-9230(98)00076-8
PMID:9865853
Abstract

Quantitative analyses of transsynaptic granule cell death subsequent to the genetically determined degeneration of Purkinje cells in the cerebellum of pcd/pcd mutant mice show that granule neuron fallout follows a typical mathematical pattern of elemental decay. Biological and theoretical connotations are discussed in light of the empirical observations and a simulation model.

摘要

对pcd/pcd突变小鼠小脑浦肯野细胞基因决定的变性后突触颗粒细胞死亡的定量分析表明,颗粒神经元减少遵循典型的元素衰变数学模式。根据实证观察和模拟模型讨论了生物学和理论内涵。

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Rate of neuronal fallout in a transsynaptic cerebellar model.跨突触小脑模型中神经元脱失率
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