Berest V P, Hatash S V
State University, Ministry of Education of Ukraine, Kharkiv.
Fiziol Zh (1994). 1998;44(5-6):89-94.
The effect of temperature (range of 4-44 degrees C) upon induced aggregation of platelets from normal subjects was studied. It was shown that temperature dependences of aggregation degree and rate have maxima. A relationship between aggregation agonist kind and some features of the temperature dependence curve of the aggregation parameters is established. It was shown that the limitation of platelet membrane lipids mobility by means of lipids peroxidation leads to the shift of maxima of the temperature dependence curve of platelet aggregation degree and rate. It was concluded that character of aggregation temperature dependence was governed by phase transition in platelet membrane lipids at room temperature.
研究了温度(4 - 44摄氏度范围)对正常受试者血小板诱导聚集的影响。结果表明,聚集程度和速率的温度依赖性存在最大值。建立了聚集激动剂种类与聚集参数温度依赖性曲线某些特征之间的关系。结果表明,通过脂质过氧化作用限制血小板膜脂质流动性会导致血小板聚集程度和速率的温度依赖性曲线最大值发生偏移。得出结论,聚集温度依赖性的特征受室温下血小板膜脂质相变的控制。