Brazhenko N A, Kostina Z I, Godes Iu E, Krokhaleva L L, Brazhenko O N, Tsareva O I, Balashova N M
Probl Tuberk. 1998(5):48-51.
The types of adaptative responses were defined, by analysing leukograms in 126 patients with tuberculous pleurisy. Assessing homeostasis by proteinograms, cellular and humoral immunity verified adaptative responses as an integral index of responsiveness. This identified 5 types of responsiveness. Abnormal (hyperactive, hyporeactive, paradoxical, and areactive) responsiveness was found in 78.6% of patients with tuberculous pleurisy. All outcomes with significant residual pleural changes were observed in patients with abnormal responsiveness. Adaptative responses may be used in the clinical setting not only for evaluation of homeostasis, but for prediction of prognosis and for organization of controlled pathogenetic therapy on an individual basis.
通过分析126例结核性胸膜炎患者的白细胞计数，确定了适应性反应的类型。通过蛋白图谱、细胞免疫和体液免疫评估内环境稳定，验证适应性反应是反应性的一个综合指标。这确定了5种反应类型。在78.6%的结核性胸膜炎患者中发现了异常（反应亢进、反应低下、矛盾反应和无反应）反应。所有有明显胸膜残留改变的结果均见于反应异常的患者。适应性反应不仅可用于临床环境中评估内环境稳定，还可用于预测预后以及组织个体化的可控病因治疗。
