Tiukhtin N S, Stogova N A, Berlova Z D, Efimova L P
Probl Tuberk. 1989(6):37-40.
Determination of antitryptic activity of blood serum and exudate in patients with tuberculous pleurisy revealed that concentrations of trypsin inhibitors were significantly increased while their activity was markedly decreased (2-3-fold) in the exudate. This indicated exhaustion of the adaptation mechanisms in the inflammatory areas, which required their local correction. Intrapleural administration of contrical increased the body's protective and adaptation potentials and treatment efficiency such as shorter times of intoxication and pleural exudation and less frequency of pronounced concomitant pleural lesions.
对结核性胸膜炎患者血清和渗出液的抗胰蛋白酶活性测定表明，渗出液中胰蛋白酶抑制剂的浓度显著升高，而其活性则明显降低（降低2 - 3倍）。这表明炎症区域的适应机制已耗尽，需要进行局部纠正。胸膜腔内注射抑肽酶可提高机体的保护和适应潜能以及治疗效果，如缩短中毒和胸膜渗出时间，减少明显伴随胸膜病变的发生频率。
