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非人灵长类动物急性胃扩张的观察

Observations on acute gastric dilatation in nonhuman primates.

作者信息

Soave O A

出版信息

Lab Anim Sci. 1978 Jun;28(3):331-4.

PMID:98666
Abstract

In the years 1967-1977 we diagnosed 23 cases of acute gastric dilatation in monkeys. Fourteen of these animals were Macaca mulatta, five Macaca fascicularis, and one each of Macaca nemestrina, Aotus trivirgatus, Saimiri sciureus, and Colobus guereza. Fourteen of the animals were males, nine were females, and all were adults or subadults. Mortality was 78% (18 of 23 animals). Thirteen of the animals had received on anesthetic, immobilizing, or tranquilizing drug 1-2 days before developing acute gastric dilatation; seven monkeys were overfed, and two had been transferred from one area to another the day prior to developing the disease. Two animals were found dead in their cages with no apparent cause for the gastric dilatation. Five Macaca mulatta and three Macaca fascicularis recovered following treatment, but two Macaca mulatta subsequently succumbed to another episode of acute gastric dilatation. Treatment consisted of evacuation of the stomach, correction of blood volume deficits and acid-base disturbances by administration of appropriate fluids, and supportive therapy for shock.

摘要

在1967年至1977年间,我们诊断出23例猴子急性胃扩张病例。其中14只为恒河猴,5只为食蟹猴,另外1只分别为豚尾猴、三带夜猴、松鼠猴和黑白疣猴。14只为雄性,9只为雌性,均为成年或亚成年猴。死亡率为78%(23只动物中有18只死亡)。13只动物在发生急性胃扩张前1 - 2天接受过麻醉、制动或镇静药物;7只猴子喂食过量,2只在发病前一天从一个区域转移到另一个区域。2只动物被发现死在笼中,胃扩张无明显病因。5只恒河猴和3只食蟹猴经治疗后康复,但2只恒河猴随后死于另一轮急性胃扩张。治疗包括胃排空、通过输注适当液体纠正血容量不足和酸碱紊乱,以及针对休克的支持性治疗。

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