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[Micro支架II(AVE)冠状动脉支架中血栓形成和再狭窄的临床、血管造影及操作预测因素]

[The clinical, angiographic and procedural predictors of thrombosis and restenosis in Micro stent II (AVE) coronary stents].

作者信息

Parma A, Lioy E, Loschiavo P, Salati A, Pucci E, Prati F, Magliocchetti N, Santoboni A

机构信息

Dipartimento di Cardioscienze, Azienda Ospedaliera San Camillo-Forlanini, Roma.

出版信息

G Ital Cardiol. 1998 Nov;28(11):1238-46.

PMID:9866801
Abstract

The aim of the study was to assess the incidence and the predictors of thrombosis and restenosis in Micro stent II AVE. In a sample of 197 stents successfully implanted in 181 consecutive patients, the incidence of thrombosis was 4.1%. The multivariate analysis showed the minimum lumen diameter post-stenting to be the only independent predictor of overall thrombosis. In fact, we found that the risk of thrombosis increases as the minimal lumen diameter decreases. Angiographic follow-up was available in 74% of the stents at 6.8 +/- 4.1 months and stent restenosis occurred in 26.2% of cases. Independent predictors of restenosis (multivariate linear discriminant analysis) were: 1) nominal stent diameter (the risk of restenosis decreases as the stent diameter increases); 2) the ratio between the diameter of the balloon carrying the stent measured at the maximum pressure/nominal stent diameter (the risk increases as the ratio decreases); 3) stented vessel (the risk increases in the following order: right coronary < circumflex < left anterior descending); 4) the American Heart Association classification of lesion morphology (the risk increases in the order A < B < C); 5) a lower risk was found in the absence of diabetes mellitus.

摘要

本研究的目的是评估Micro stent II AVE中血栓形成和再狭窄的发生率及预测因素。在181例连续患者成功植入的197枚支架样本中,血栓形成的发生率为4.1%。多变量分析显示,支架置入后最小管腔直径是总体血栓形成的唯一独立预测因素。事实上,我们发现随着最小管腔直径减小,血栓形成的风险增加。74%的支架在6.8±4.1个月时进行了血管造影随访,26.2%的病例发生了支架再狭窄。再狭窄的独立预测因素(多变量线性判别分析)为:1)标称支架直径(随着支架直径增加,再狭窄风险降低);2)承载支架的球囊在最大压力下测量的直径与标称支架直径之比(随着该比值降低,风险增加);3)置入支架的血管(风险按以下顺序增加:右冠状动脉<回旋支<左前降支);4)美国心脏协会病变形态学分类(风险按A<B<C顺序增加);5)未患糖尿病时风险较低。

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