Salvati M, Cervoni L, Raguso M
Dipartimento di Scienze Neurologiche, IRCCS, Pozzilli, Isernia.
Minerva Ginecol. 1998 Oct;50(10):445-7.
Brain metastases from endometrial carcinoma rarely involve the nervous system and are solitary in exceptional cases (< 1% of cases). Two cases of solitary cerebral metastasis from endometrial carcinoma are described. Two patients, submitted to the therapeutic protocol established for endometrial carcinoma, underwent surgery, radiotherapy and chemotherapy for solitary cerebral metastasis after at average interval of 18 months. Average survival was 46 months and death was due to progression of the systemic disease. An examination of our cases and those described in the literature has shown that, although these metastasis do not respond well to therapeutic treatment, a better outcome may be achieved by combined treatment consisting of surgery, radiotherapy and chemotherapy.
子宫内膜癌脑转移很少累及神经系统，仅在极少数情况下（<1%的病例）为孤立性转移。本文描述了2例子宫内膜癌孤立性脑转移病例。2例患者按照既定的子宫内膜癌治疗方案，在平均间隔18个月后，针对孤立性脑转移接受了手术、放疗和化疗。平均生存期为46个月，死亡原因是全身性疾病进展。对我们的病例以及文献中描述的病例进行检查后发现，尽管这些转移对治疗反应不佳，但通过手术、放疗和化疗联合治疗可能会取得更好的效果。
