He A, Fu Y, Li H
Department of Surgery, Second Affiliated Hospital, Hunan Medical University, Changsha.
Hunan Yi Ke Da Xue Xue Bao. 1997;22(4):287-90.
To study the effect of tendon healing and adhesion after tendon repaired using the artificial biological skin (Biofill) produced in Brazil, we divided randomly 46 rats [correction of mice] into groups, compared the pelvic limbs with themselves, observed by eyes and light microscopy, and made biomechanical and histological detection in 1st, 2nd, 3rd and 4th weeks postsurgically. The results showed that the speed and strength of tendon healing had light affect in three weeks after operation, and had no difference between experimental groups and control groups after 4 weeks. It is indicated that artificial skin "Biofill" can effectively prevent tendon adhesion after tendon repaired and have not obviously influenced in the intrinsic self-healing process of tendon.
为研究巴西生产的人工生物皮肤（Biofill）修复肌腱后对肌腱愈合及粘连的影响，我们将46只大鼠随机分组，以其自身双侧后肢作对照，术后第1、2、3、4周分别进行大体及光镜观察，并作生物力学及组织学检测。结果显示，术后3周内人工生物皮肤对肌腱愈合速度及强度影响轻微，4周后实验组与对照组无明显差异。提示人工皮肤Biofill能有效防止肌腱修复后粘连，对肌腱自身愈合过程无明显影响。
