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[戊型肝炎病毒血清IgG抗体水平的检测]

[Detection of the level of serum IgG antibody to hepatitis E virus].

作者信息

Xie Y, Tan D, Gan X

机构信息

Department of Infectious Disease, Xiangya Hospital, Hunan Medical University, Changsha.

出版信息

Hunan Yi Ke Da Xue Xue Bao. 1997;22(3):223-5.

PMID:9868119
Abstract

The levels of serum IgG antibody to hepatitis E virus (anti-HEV-IgG) was detected in serum specimens from 50 patients with acute sporadic hepatitis E and 20 healthy donors who were positive for anti-HEV-IgG by ELISA titration. The results showed that the level of anti-HEV-IgG in acute hepatitis E patients was significantly higher than that in healthy donors and the average titer is 1:121 and 1:22, respectively (P < 0.01). So acute viral hepatitis E should be diagnozed when the titer of anti-HEV-IgG was over 1:40.

摘要

采用ELISA滴定法检测了50例急性散发性戊型肝炎患者和20例抗戊型肝炎病毒IgG(anti-HEV-IgG)阳性健康献血者血清标本中anti-HEV-IgG水平。结果显示,急性戊型肝炎患者的anti-HEV-IgG水平显著高于健康献血者,平均滴度分别为1:121和1:22(P<0.01)。因此,当anti-HEV-IgG滴度超过1:40时,应诊断为急性戊型病毒性肝炎。

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