Deng F, Tang Z, Liu B, Wang C, Jian X
Department of Oral and Maxillorfacial Surgery, Xiangya Hospital, Hunan Medical University, Changsha.
Hunan Yi Ke Da Xue Xue Bao. 1997;22(3):229-32.
To analyse the anaerobic infection of maxillofacial surgery and estimate the efficacy of antianaerobic therapy, 45 patients were divided into two groups, tinidazole group and metronidazole group. Bacterial culture was positive before treating in all cases. There were Bacillus Melaniogenicus, Veillonella, Peptococcus and Peptostreptococus, etc. There was excellent efficacy in the treatment of maxillofacial anaerobic infection by tinidazole intravenously. After treatment, the result of bacterial examination was negative. The healing rate was 96.4% in 28 cases which used tinidazol, but 82.4% in control group which used metronidazole. The value of white blood cell and the function of liver and kidney pro- and post-treatment were not significantly different (P < 0.05) by comparision.
为分析颌面部手术的厌氧菌感染情况并评估抗厌氧菌治疗的疗效，将45例患者分为两组，即替硝唑组和甲硝唑组。所有病例治疗前细菌培养均为阳性。有产黑色素杆菌、韦荣球菌、消化球菌和消化链球菌等。静脉滴注替硝唑治疗颌面部厌氧菌感染疗效极佳。治疗后细菌检查结果为阴性。使用替硝唑的28例患者愈合率为96.4%，而使用甲硝唑的对照组愈合率为82.4%。比较治疗前后白细胞值及肝肾功能，差异无统计学意义（P<0.05）。
