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聚四氟乙烯用于治疗严重缺血性膝上股腘动脉搭桥术的长期效果

Long term results of polytetrafluoroethylene in above knee femoropopliteal bypass for critical ischaemia.

作者信息

Kavanagh E G, O'Riordain D S, Buckley D J, O'Donnell J A

机构信息

Department of Surgery, Cork University Hospital.

出版信息

Ir J Med Sci. 1998 Oct-Dec;167(4):221-4. doi: 10.1007/BF02937416.

Abstract

Ninety-six consecutive above-knee femoropopliteal bypasses, using polytetrafluoroethylene (PTFE) preferentially, were performed for limb-threatening ischaemia. Cumulative primary graft patency was 68 per cent, 49 per cent and 36 per cent and limb salvage 93 per cent, 85 per cent and 75 per cent at 1, 3 and 5 yr respectively. As a result of poor long term survival (51 per cent at 5 yr), and the healing of remedial lesions before graft occlusion, 68 patients (72 per cent) required no further intervention. Eighteen secondary bypasses were undertaken, 12 using ipsilateral saphenous vein. In this group of elderly patients with poor life expectancy, where a limited operation is desirable, the use of PTFE provided excellent limb salvage with low morbidity. Although we can no longer justify our continued use of PTFE in every case of critical ischaemia because of its inferior patency to autogenous vein, we continue to use it preferentially in patients whose lifespan is likely to be short and in cases where a remedial lesion is present.

摘要

对96例因肢体缺血严重而危及肢体的患者连续进行了膝上股腘动脉搭桥手术,优先使用聚四氟乙烯(PTFE)。1年、3年和5年时,原发性移植血管的累积通畅率分别为68%、49%和36%,肢体挽救率分别为93%、85%和75%。由于长期生存率较低(5年时为51%),且在移植血管闭塞前补救性病变已愈合,68例患者(72%)无需进一步干预。进行了18例二次搭桥手术,其中12例使用同侧大隐静脉。在这组预期寿命较短的老年患者中,在需要进行有限手术的情况下,使用PTFE可实现良好的肢体挽救,且发病率较低。尽管由于PTFE的通畅性不如自体静脉,我们不能再为在每例严重缺血病例中持续使用它找到合理依据,但我们仍继续优先在寿命可能较短的患者以及存在补救性病变的病例中使用它。

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