Sakamoto Y, Nakajima T, Misawa S, Ishikawa H, Itoh Y, Nakashima T, Okanoue T, Kashima K, Tsuji T
Department of Gastroenterology, Kyoto Prefectural Yosanoumi Hospital.
Intern Med. 1998 Nov;37(11):927-9. doi: 10.2169/internalmedicine.37.927.
A case of acute liver damage by ingestion of Aplysia kurodai, a sea hare is reported. A 40-year-old man, complaining of vomiting and pyrexia after eating a sea hare, was admitted. Laboratory data showed mild liver damage with sustained elevations of aminotransferases. Microscopic findings in the liver biopsy specimen revealed characteristic apoptotic hepatocytes accompanied by mitotic hepatocytes. It is suggested that bioactive substances in the sea hare might induce such apoptosis of hepatocytes in the liver.
本文报告一例因食用海兔（黑指纹海兔）导致急性肝损伤的病例。一名40岁男性在食用海兔后出现呕吐和发热症状，随后入院。实验室检查数据显示转氨酶持续升高，存在轻度肝损伤。肝活检标本的显微镜检查结果显示，有特征性的凋亡肝细胞，同时伴有有丝分裂的肝细胞。提示海兔中的生物活性物质可能诱导肝脏中肝细胞发生此类凋亡。
