Wu C J, Chen H L, Song Y M, Sheu W H, Chen S H
Division of Endocrinology and Metabolism in Department of Medicine, Taichung Veterans General Hospital, Taiwan, ROC.
Intern Med. 1998 Nov;37(11):955-7. doi: 10.2169/internalmedicine.37.955.
We report a rare case of mixed medullary-follicular carcinoma and papillary carcinoma of the same thyroid. A 27-year-old Chinese female complained of a single thyroid nodule for 2-3 months. Needle aspiration revealed suspicious papillary carcinoma and thyroidectomy performed later showed mixed medullary-follicular carcinoma and papillary carcinoma of the same thyroid which was extremely rare. Whether neoplastic transformation is due to tumorigenic stimulus or just due to the collision phenomenon is still controversial for its etiology.
我们报告了一例罕见的同一甲状腺内混合性髓样-滤泡癌和乳头状癌病例。一名27岁的中国女性主诉单个甲状腺结节2至3个月。针吸活检显示可疑乳头状癌,随后进行的甲状腺切除术显示同一甲状腺内存在混合性髓样-滤泡癌和乳头状癌,这极为罕见。关于其病因,肿瘤转化是由于致瘤刺激还是仅仅由于碰撞现象仍存在争议。