Kapur A, Ma C M, Mok E C, Findley D O, Boyer A L
Department of Radiation Oncology, Stanford University School of Medicine, CA 94305-5105, USA.
Phys Med Biol. 1998 Dec;43(12):3479-94. doi: 10.1088/0031-9155/43/12/007.
The purpose of this study was to investigate the application of the Monte Carlo technique to the calculation and analysis of output factors for electron beams used in radiotherapy. The code EGS4/BEAM was used to obtain phase-space files for 6, 12 and 20 MeV clinical electron beams from a scattering-foil linac (Varian Clinac 2100C) for a clinically representative range of applicator and square or rectangular insert combinations. The source-to-surface distance used was 100 cm. The field sizes ranged from 1 x 1 cm2 to 20 x 20 cm2. These phase-space files were analysed to study the intrinsic beam characteristics and used as source input for relative dose and output factor computations in homogeneous water phantoms using the code EGS4/DOSXYZ. The calculated relative central-axis depth-dose and transverse dose profiles at various depths of clinical interest agreed with the corresponding measured dose profiles to within 2% of the maximum dose. Calculated output factors for the fields studied agreed with measured output factors to about 2%. This demonstrated that for the Varian Clinac 2100C linear accelerator, electron beam dose calculations in homogeneous water phantoms can be performed accurately at the 2% level using Monte Carlo simulations.
本研究的目的是探讨蒙特卡罗技术在放射治疗中电子束输出因子计算与分析方面的应用。使用代码EGS4/BEAM,针对来自散射箔直线加速器(瓦里安Clinac 2100C)的6、12和20 MeV临床电子束,获取适用于临床代表性范围的施源器以及方形或矩形插入物组合的相空间文件。使用的源皮距为100 cm。射野大小范围从1×1 cm2至20×20 cm2。对这些相空间文件进行分析以研究固有束流特性,并将其用作使用代码EGS4/DOSXYZ在均匀水模体中进行相对剂量和输出因子计算的源输入。在各种临床关注深度处计算得到的相对中心轴深度剂量和横向剂量分布与相应的测量剂量分布在最大剂量的2%范围内一致。所研究射野的计算输出因子与测量输出因子约2%相符。这表明对于瓦里安Clinac 2100C直线加速器,使用蒙特卡罗模拟可在2%的精度水平上准确进行均匀水模体中的电子束剂量计算。