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大鼠颞下颌关节创伤性滑膜炎的发展及组织学特征

Development and histologic characteristics of synovitis induced by trauma in the rat temporomandibular joint.

作者信息

Muto T, Kawakami J, Kanazawa M, Kaku T, Yajima T

机构信息

Department of Oral and Maxillofacial Surgery, School of Dentistry, Health Sciences University of Hokkaido, Japan.

出版信息

Int J Oral Maxillofac Surg. 1998 Dec;27(6):470-5. doi: 10.1016/s0901-5027(98)80041-6.

Abstract

Histopathological changes caused by trauma to the rat temporomandibular joint synovium were examined by light microscopy. The trauma was induced by forced hypermobility of the condyle. Pathological changes of the synovium were found primarily in the anterior pouch of the upper joint compartment. The main findings included surface cell proliferation, increased capillary hyperemia, fibrin deposits on the surfaces of inflamed synovial membranes, and fibrinous adhesion between closely opposed synovial membranes. A gradual change from fibrinous adhesion to fibrous adhesion was also seen.

摘要

通过光学显微镜检查大鼠颞下颌关节滑膜创伤引起的组织病理学变化。创伤是由髁突的强迫性活动过度诱发的。滑膜的病理变化主要见于上关节腔的前隐窝。主要发现包括表面细胞增殖、毛细血管充血增加、炎症滑膜表面的纤维蛋白沉积以及紧密相对的滑膜之间的纤维蛋白粘连。还观察到从纤维蛋白粘连到纤维粘连的逐渐变化。

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