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颞下颌关节关节镜活检标本中的滑膜炎症:文献综述及组织学分级系统建议

Synovial inflammation in arthroscopically obtained biopsy specimens from the temporomandibular joint: a review of the literature and a proposed histologic grading system.

作者信息

Gynther G W, Dijkgraaf L C, Reinholt F P, Holmlund A B, Liem R S, de Bont L G

机构信息

Department of Oral and Maxillofacial Surgery, Huddinge University Hospital, Karolinska Institute, Sweden.

出版信息

J Oral Maxillofac Surg. 1998 Nov;56(11):1281-6; discussion 1287. doi: 10.1016/s0278-2391(98)90609-7.

DOI:10.1016/s0278-2391(98)90609-7
PMID:9820216
Abstract

Data indicate that the synovial lining of the temporomandibular joint (TMJ) in some respects differs from other joints. The normal variation in morphology of the synovial lining of the TMJ is quite great, whereas the variation in pattern of pathologic changes appears to be relatively small (ie, synovial inflammation is not of the severity as that in other joints). In the current review, a system for histologic grading of synovial inflammation is proposed. The system is based on semiquantitative evaluation of the following set of parameters: 1) synovial lining cell layers; 2) vascularity (number or size of vascular profiles); and 3) Inflammatory cell infiltrate (commonly lymphocytes).

摘要

数据表明,颞下颌关节(TMJ)的滑膜衬里在某些方面与其他关节不同。颞下颌关节滑膜衬里形态的正常变异相当大,而病理变化模式的变异似乎相对较小(即滑膜炎症的严重程度不如其他关节)。在当前的综述中,提出了一种滑膜炎症的组织学分级系统。该系统基于对以下一组参数的半定量评估:1)滑膜衬里细胞层;2)血管形成(血管轮廓的数量或大小);3)炎性细胞浸润(通常为淋巴细胞)。

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