Marigo F A, Finger P T, McCormick S A, Iezzi R, Esaki K, Ishikawa H, Seedor J, Liebmann J M, Ritch R
Department of Ophthalmology, New York Eye and Ear Infirmary, New York, USA.
Arch Ophthalmol. 1998 Dec;116(12):1569-75. doi: 10.1001/archopht.116.12.1569.
To correlate the clinical, histopathologic, and ultrasound biomicroscopic characteristics of anterior segment implantation cysts.
We performed a retrospective review of 7 cases of secondary anterior segment implantation cysts. We reviewed the clinical history, visual acuity, clinical findings, and ultrasound biomicroscopic characteristics in all cases. Histopathologic correlation was possible in 4 cases.
Six eyes had been subjected to major trauma prior to cyst formation. Trauma was noted as blunt in 3 eyes and surgical in 3 eyes. The diagnosis was confirmed in 1 eye when conjunctival cells were aspirated on fine needle biopsy. Ultrasound biomicroscopy revealed large (mean +/- SD greatest diameter, 4.7 +/- 0.9 mm) cystic tumors. In 1 patient, a cyst-related indentation of the anterior lens surface was seen. Ultrasonographic evaluations of internal reflectivity revealed thick, moderately reflective cyst walls encapsulating a relatively hypoechoic core. In 3 cases, the cyst contents consisted of variably reflective material. The other 4 were completely sonolucent. Histopathologic correlation showed that the cyst walls were lined with stratified squamous epithelium. The moderately reflective cyst contents were found to be degenerated conjunctival cells with inflammatory foci and cholesterol crystals. The sonolucent regions correlated with inflammatory cells and fluid.
This study demonstrates that implantation cysts are unilateral, large, and thick walled. They may be sonolucent or exhibit variable internal reflectivity. These findings as well as the extent of anterior segment involvement (particularly posterior extension) could be evaluated by ultrasound biomicroscopy prior to surgery.
关联眼前段植入性囊肿的临床、组织病理学及超声生物显微镜特征。
我们对7例继发性眼前段植入性囊肿进行了回顾性研究。我们回顾了所有病例的临床病史、视力、临床发现及超声生物显微镜特征。4例病例可进行组织病理学关联。
6只眼在囊肿形成前遭受过严重外伤。3只眼为钝挫伤，3只眼为手术伤。1只眼经细针穿刺活检吸出结膜细胞后确诊。超声生物显微镜显示为大的（平均±标准差最大直径，4.7±0.9 mm）囊性肿瘤。1例患者可见囊肿相关的晶状体前表面压痕。内部反射率的超声评估显示，厚的、中等反射性的囊肿壁包裹着一个相对低回声的核心。3例病例中，囊肿内容物由不同反射性的物质组成。另外4例完全无回声。组织病理学关联显示囊肿壁内衬复层鳞状上皮。中等反射性的囊肿内容物为退变的结膜细胞，伴有炎症灶和胆固醇结晶。无回声区与炎症细胞和液体相关。
本研究表明植入性囊肿为单侧、大且壁厚。它们可能无回声或表现出不同的内部反射率。这些发现以及眼前段受累程度（尤其是向后延伸）可在手术前通过超声生物显微镜进行评估。
