Gündüz Kaan, Hoşal Banu M, Zilelioğlu Güler, Günalp Ilhan
Department of Ophthalmology, Ankara University Faculty of Medicine, Ankara, Turkey.
Ophthalmologica. 2007;221(5):305-12. doi: 10.1159/000104760.
To report the ultrasound biomicroscopy (UBM) findings of anterior segment tumors and simulating conditions.
Thirty-five patients underwent UBM. Of those, 16 had histopathologically or cytopathologically diagnosed tumors, and 19 had clinically diagnosed lesions.
The study material comprised 13 iris pigment epithelial (IPE) cysts, 7 ciliary body melanomas, 4 iris melanomas, 4 iris nevi, 3 intraocular invasions of conjunctival squamous cell carcinoma, 2 ring melanomas of the anterior chamber angle, 1 medulloepithelioma and 1 pars plana cyst. On UBM, all IPE cysts presented as cystic lesions with a thin cyst wall and no solid components. All ciliary body melanomas showed low to medium reflectivity, with cavitation in one case and extraocular extension in another. Iris melanomas presented as anterior (stromal) iris lesions with medium to high internal reflectivity. There was irregularity and convex bowing of the posterior iris plane in iris melanomas, a feature not seen in iris nevi. Intraocular invasion of conjunctival squamous cell carcinoma was evidenced as areas of medium to high reflectivity in the ciliary body and iris, loss of the acute angle shape and highly reflective spots in the anterior chamber.
UBM was particularly useful in the diagnosis of IPE cysts, in the visualization of small ciliary body melanomas, in the differentiation of iris melanomas from iris nevi and in the demonstration of intraocular invasion from conjunctival squamous cell carcinoma.
报告眼前节肿瘤及类似病变的超声生物显微镜（UBM）检查结果。
35例患者接受了UBM检查。其中16例经组织病理学或细胞病理学诊断为肿瘤，19例为临床诊断的病变。
研究材料包括13个虹膜色素上皮（IPE）囊肿、7例睫状体黑色素瘤、4例虹膜黑色素瘤、4例虹膜痣、3例结膜鳞状细胞癌的眼内侵犯、2例前房角环状黑色素瘤、1例髓上皮瘤和1例睫状体平坦部囊肿。在UBM检查中，所有IPE囊肿均表现为囊壁薄且无实性成分的囊性病变。所有睫状体黑色素瘤均表现为低至中等回声，1例有液化，1例有眼外扩展。虹膜黑色素瘤表现为虹膜前部（基质）病变，内部回声为中等至高回声。虹膜黑色素瘤的虹膜后表面不规则且呈凸形弯曲，这一特征在虹膜痣中未见。结膜鳞状细胞癌的眼内侵犯表现为睫状体和虹膜中等至高回声区域、前房角形态消失及前房内高回声光斑。
UBM在IPE囊肿的诊断、小睫状体黑色素瘤的可视化、虹膜黑色素瘤与虹膜痣的鉴别以及结膜鳞状细胞癌眼内侵犯的显示方面特别有用。
