Miani C, Baratieri A, Deli R
Minerva Stomatol. 1978 Apr-Jun;27(2):87-93.
Odontomix (reg'd) cement was used at the bottom of cavities prepared in healthy dog canines in a attempt to prevent pulp and dentine alterations caused by the preparation and filling of cavities. 24 dogs were used along with 24 controls. I.v. tetracycline was afterwards given 10 times at weekly intervals. Examination of tetracycline labelling under the cavities showed that the cement caused pulp and dentine changes in confined areas, though it has not yet been possible to determine whether these are due to the corticosteroid, the antibiotic, or the excipient employed in the preparation.
使用Odontomix(注册)粘固剂置于健康犬类犬齿制备的窝洞底部,以试图防止窝洞制备和充填引起的牙髓和牙本质改变。使用了24只狗和24只对照。随后静脉注射四环素,每周1次,共10次。对窝洞下方四环素标记的检查表明,该粘固剂在受限区域引起了牙髓和牙本质变化,尽管尚未能够确定这些变化是由于皮质类固醇、抗生素还是制剂中使用的辅料所致。