一名患有t(11;19)(q14 - 21;p12)的肺黏液表皮样癌患儿。
A child with a t(11;19)(q14-21;p12) in a pulmonary mucoepidermoid carcinoma.
作者信息
Stenman G, Petursdottir V, Mellgren G, Mark J
机构信息
Department of Pathology, Göteborg University, Sahlgrenska University Hospital, Sweden.
出版信息
Virchows Arch. 1998 Dec;433(6):579-81. doi: 10.1007/s004280050293.
We report on a mucoepidermoid carcinoma (MEC) of the lung in a 6-year-old girl with a t(11;19)(q14-21;p12) as the sole karyotypic abnormality. An apparently identical t(11;19) has been reported previously in a MEC originating from the major and minor salivary glands. Our findings indicate that the t(11;19) is intimately associated with the mucoepidermoid phenotype and may be used as a diagnostic marker for this tumour type.
我们报告了一名6岁女孩的肺黏液表皮样癌（MEC），其唯一的核型异常为t(11;19)(q14 - 21;p12)。先前曾有报道称，源自大、小唾液腺的黏液表皮样癌中存在明显相同的t(11;19)。我们的研究结果表明，t(11;19)与黏液表皮样表型密切相关，可作为这种肿瘤类型的诊断标志物。
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