Davy K W, Kalachandra S, Pandain M S, Braden M
IRC in Biomedical Materials, University of London, Department of Biomaterials in Relation to Dentistry, St. Bartholomews and the Royal London School of Medicine and Dentistry, UK.
Biomaterials. 1998 Nov;19(22):2007-14. doi: 10.1016/s0142-9612(98)00047-7.
The synthesis of three novel dimethacrylate esters for use as the monomer phase in dental composites was studied. The monomers were prepared by the reaction of glycidyl methacrylate with phthalic, isophthalic and terephthalic acids, respectively, and the reaction products were found to be mixtures of isomers. The monomers obtained from the reaction of phthalic and isophthalic acids were low-viscosity liquids and the relationship between viscosity and molecular structure was studied. The low viscosity of these di-hydroxyl containing monomers was shown to be due to intramolecular hydrogen bonding. This reduced monomer viscosity compared with BisGMA allowed a reduction in the quantity of diluent monomer triethyleneglycoldimethacrylate (TEGDMA) required to give standard viscosities of 1 and 2 Pas resulting in a modest decrease (ca. 10%) in polymerization shrinkage compared with that exhibited by BisGMA/TEGDMA solutions of equivalent viscosities. A number of properties relevant to the use of these as potential core monomers in dental composites were determined for both monomer and polymer systems.
研究了三种新型二甲基丙烯酸酯的合成，它们用作牙科复合材料的单体相。这些单体分别通过甲基丙烯酸缩水甘油酯与邻苯二甲酸、间苯二甲酸和对苯二甲酸反应制备，发现反应产物为异构体混合物。由邻苯二甲酸和间苯二甲酸反应得到的单体是低粘度液体，并研究了粘度与分子结构之间的关系。这些含二羟基的单体的低粘度被证明是由于分子内氢键作用。与双甲基丙烯酸缩水甘油酯（BisGMA）相比，这种降低的单体粘度使得给出1和2帕斯卡标准粘度所需的稀释单体三乙二醇二甲基丙烯酸酯（TEGDMA）的量减少，与同等粘度的BisGMA/TEGDMA溶液相比，聚合收缩率适度降低（约10%）。针对单体和聚合物体系，测定了与这些物质作为牙科复合材料潜在核心单体使用相关的一些性能。
