Vaidyanathan Tritala K, Vaidyanathan Jayalakshmi
Department of Restorative Dentistry, Rutgers School of Dental MedicineNewarkNJUSA.
Acta Biomater Odontol Scand. 2015 Sep 18;1(2-4):59-65. doi: 10.3109/23337931.2015.1085806. eCollection 2015 Dec.
: The goal of this study was to characterize the light curing characteristics of a new oligomer PEM-665 designed to be used as an alternative monomer to BisGMA. : PEM-665 (P) and BisGMA (B) solutions were prepared with triethylene glycol dimethacrylate (T) diluent in different weight proportions (70/30 and 50/50). Solutions containing 70% P and 30% T were designated as 70PT, 70%B and 30%T as 70BT, 50%P and 50%T as 50PT and 50%B and 50%T as 50BT. The initiators were CQ (EDMAB was used as amine accelerator for CQ) and DPO in 1% concentration. Eight solutions were prepared in a factorial design: 70PT/DPO; 70PT/CQ; 50PT/DPO; 50PT/CQ; 70BT/DPO; 70BT/CQ; 50BT/DPO; 50BT/CQ. BISCO VIP visible light was used to cure the monomer solutions using 30 s exposure time and 400 W power setting. TA Instruments Differential Scanning Calorimeter (DSC 2910) was used to determine the heat of cure (J/g) during polymerization at 37 °C, from which molar heat of cure (kJ/mole) and %Conversion values were estimated. : Range of mean values as a function monomer selections were: heat of cure (J/g): 161.7 for 70PT/DPO system to 198.6 for 50BT/CQ system; molar heat of cure (kJ/mole): 67.3 for 70BT/DPO to 78.86 for 50PT/CQ; % conversion: 59.9 for 70BT/DPO to 70.3 for 50PT/CQ. Analysis of variance and Tukey HSD pairwise contrast showed statistically significant differences between % conversion means of PEM and BisGMA mixtures, with PEM mixtures showing significantly higher mean values. : The results suggest that PEM-665 is a promising candidate material for dental polymer applications.
本研究的目的是表征一种新型低聚物PEM - 665的光固化特性，该低聚物被设计用作BisGMA的替代单体。用二缩三乙二醇二甲基丙烯酸酯（T）稀释剂按不同重量比例（70/30和50/50）制备PEM - 665（P）和BisGMA（B）溶液。含70% P和30% T的溶液指定为70PT，70% B和30% T为70BT，50% P和50% T为50PT，50% B和50% T为50BT。引发剂为浓度1%的CQ（EDMAB用作CQ的胺促进剂）和DPO。采用析因设计制备了八种溶液：70PT/DPO；70PT/CQ；50PT/DPO；50PT/CQ；70BT/DPO；70BT/CQ；50BT/DPO；50BT/CQ。使用BISCO VIP可见光以30秒曝光时间和400瓦功率设置固化单体溶液。使用TA仪器差示扫描量热仪（DSC 2910）测定37℃聚合过程中的固化热（J/g），据此估算摩尔固化热（kJ/摩尔）和转化率百分比值。作为单体选择函数的平均值范围为：固化热（J/g）：70PT/DPO体系为161.7至50BT/CQ体系为198.6；摩尔固化热（kJ/摩尔）：70BT/DPO为67.3至50PT/CQ为78.86；转化率百分比：70BT/DPO为59.9至50PT/CQ为70.3。方差分析和Tukey HSD成对对比显示，PEM和BisGMA混合物的转化率平均值之间存在统计学显著差异，PEM混合物的平均值显著更高。结果表明，PEM - 665是牙科聚合物应用中有前景的候选材料。
