Schettini M, Diana M, Gallucci M
Division of Urology, Cristo Re Hospital, Rome, Italy.
Int Surg. 1998 Jul-Sep;83(3):257-61.
Urinary incontinence has a significant impact on the quality of life for patients. The introduction of the AMS 800 artificial urinary sphincter by American Medical Systems (Minnetonka, MN, USA) has revolutionized the treatment of urinary incontinence due to pure sphincteric incompetence.
From April 1989 to October 1997, a total of 52 patients (42 men and 3 women) underwent implantation of the AMS 800 artificial sphincter. Patient age ranged from 31 to 87 years (mean 69.5 years). They all were suffering from urinary incontinence caused by sphincteric damage, always of iatrogenic origin. Follow-up was 5-110 months, with a mean of 35 months.
The restoration of continence was complete for 35 patients and allowed them all to return to their normal life. 7 of the patients who had a successful implant died because of other problems. For 2 patients follow-up was not available. Explantation was performed 8 times: in 5 male patients the device was removed because of periprosthetic infections; in 1 female patient with ileal neobladder, because of serious urethral necrosis; and in 2 male patients because of an urethral erosion.
The AMS 800 artificial urinary sphincter is the most efficacious treatment currently available for urinary incontinence due to pure sphincteric incompetence. Implanted patients achieved acceptable urinary control. The implantation is associated with 2 distinct complications: surgical and mechanical.
尿失禁对患者的生活质量有重大影响。美国美敦力公司（美国明尼苏达州明尼通卡）推出的AMS 800人工尿道括约肌彻底改变了因单纯括约肌功能不全导致的尿失禁的治疗方法。
1989年4月至1997年10月，共有52例患者（42例男性和3例女性）接受了AMS 800人工括约肌植入术。患者年龄在31岁至87岁之间（平均69.5岁）。他们均患有由括约肌损伤导致的尿失禁，损伤均为医源性。随访时间为5至110个月，平均35个月。
35例患者实现了完全控尿，能够恢复正常生活。7例植入成功的患者因其他问题死亡。2例患者失访。进行了8次取出手术：5例男性患者因假体周围感染取出装置；1例回肠新膀胱女性患者因严重尿道坏死取出；2例男性患者因尿道糜烂取出。
AMS 800人工尿道括约肌是目前治疗因单纯括约肌功能不全导致的尿失禁最有效的方法。植入患者实现了可接受的排尿控制。植入手术伴有两种不同的并发症：手术相关并发症和机械相关并发症。
