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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Duncia J V, Santella J B, Higley C A, VanAtten M K, Weber P C, Alexander R S, Kettner C A, Pruitt J R, Liauw A Y, Quan M L, Knabb R M, Wexler R R

DuPont Merck Pharmaceutical Company, Wilmington, DE 19880-0500, USA.

Bioorg Med Chem Lett. 1998 Apr 7;8(7):775-80. doi: 10.1016/s0960-894x(98)00104-8.

Substituted pyrazoles, 1,2,4-triazoles, and tetrazoles are good surrogates for cis-amide bonds in a series of boronate ester thrombin inhibitors.

在一系列硼酸酯凝血酶抑制剂中，取代吡唑、1,2,4-三唑和四唑是顺式酰胺键的良好替代物。

Duncia J V, Santella J B, Higley C A, VanAtten M K, Weber P C, Alexander R S, Kettner C A, Pruitt J R, Liauw A Y, Quan M L, Knabb R M, Wexler R R

DuPont Merck Pharmaceutical Company, Wilmington, DE 19880-0500, USA.

Bioorg Med Chem Lett. 1998 Apr 7;8(7):775-80. doi: 10.1016/s0960-894x(98)00104-8.

Substituted pyrazoles, 1,2,4-triazoles, and tetrazoles are good surrogates for cis-amide bonds in a series of boronate ester thrombin inhibitors.

在一系列硼酸酯凝血酶抑制剂中，取代吡唑、1,2,4-三唑和四唑是顺式酰胺键的良好替代物。