Synthesis and antiviral activity of novel isodideoxy nucleosides with exocyclic methylene.
作者信息
Jeong L S, Yoo S J
机构信息
Laboratory of Medicinal Chemistry, College of Pharmacy, Ewha Womans University, Seoul, Korea.
出版信息
Bioorg Med Chem Lett. 1998 Apr 7;8(7):847-52. doi: 10.1016/s0960-894x(98)00122-x.
PMID:9871553
Abstract
Novel isodideoxy nucleosides with exocyclic methylene were synthesized starting from L-xylose utilizing anomeric demethoxylation, Wittig reaction and Mitsunobu reaction as key steps and evaluated for antiviral activity.
摘要
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