Ram V J, Goel A, Patnaik G K
Division of Medicinal Chemistry, Central Drug Research Institute, Lucknow, India.
Bioorg Med Chem Lett. 1998 Mar 3;8(5):469-72. doi: 10.1016/s0960-894x(98)00061-4.
Functionalized 1,3-teraryls, synthesized through ring transformation of 6-aryl-3-carbomethoxy-4-methylthio-2H-pyran-2-one from arylketone have been screened for their hepatoprotective activity and of them have demonstrated significant protection in animal model.
通过芳基酮对6-芳基-3-甲氧基羰基-4-甲硫基-2H-吡喃-2-酮进行环转化合成的功能化1,3-三芳基化合物已被筛选其肝保护活性，其中一些在动物模型中显示出显著的保护作用。
