Ram V J, Goel A
Medicinal Chemistry, Central Drug Research Institute, Lucknow, 226001, India.
Curr Med Chem. 1999 Mar;6(3):217-54.
The liver plays a significant role not only in metabolism and disposition of the chemicals to which it is exposed directly or indirectly but also plays a pivotal role in the metabolism of fats, carbohydrates, proteins and immunomodulations. The impairment of liver generally results from viral or portozoal infections, excessive use of alcohol, drugs and xenobiotics. This review provides an overall view about the past and present status of the hepatoprotectants resulted from synthetic and plant origins.
肝脏不仅在直接或间接接触的化学物质的代谢和处置中发挥重要作用，而且在脂肪、碳水化合物、蛋白质的代谢以及免疫调节中也起着关键作用。肝脏损伤通常由病毒或寄生虫感染、过度饮酒、药物和外源性物质引起。本综述全面介绍了合成来源和植物来源的保肝剂的过去和现状。
