米曲霉和酱油曲霉中黄曲霉毒素生物合成基因的同源物及 aflR 序列
Homologs of aflatoxin biosynthesis genes and sequence of aflR in Aspergillus oryzae and Aspergillus sojae.
作者信息
Watson A J, Fuller L J, Jeenes D J, Archer D B
机构信息
Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, United Kingdom.
出版信息
Appl Environ Microbiol. 1999 Jan;65(1):307-10. doi: 10.1128/AEM.65.1.307-310.1999.
Abstract
The presence, but not expression, of homologs of three structural genes and a regulatory gene necessary for aflatoxin biosynthesis in Aspergillus parasiticus and A. flavus was shown for A. oryzae and A. sojae. Homologs of the regulatory gene aflR were cloned and sequenced from A. oryzae and A. sojae.
摘要
米曲霉和酱油曲霉中已证实存在寄生曲霉和黄曲霉中黄曲霉毒素生物合成所需的三个结构基因和一个调控基因的同源物，但这些同源物不表达。已从米曲霉和酱油曲霉中克隆并测序了调控基因aflR的同源物。
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本文引用的文献
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Conservation of structure and function of the aflatoxin regulatory gene aflR from Aspergillus nidulans and A. flavus.构巢曲霉和黄曲霉中黄曲霉毒素调控基因aflR的结构与功能保守性
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Twenty-five coregulated transcripts define a sterigmatocystin gene cluster in Aspergillus nidulans.25个共调控转录本定义了构巢曲霉中的一个柄曲霉素基因簇。
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Hybridization of genes involved in aflatoxin biosynthesis to DNA of aflatoxigenic and non-aflatoxigenic aspergilli.黄曲霉毒素生物合成相关基因与产黄曲霉毒素和不产黄曲霉毒素曲霉菌DNA的杂交。
Appl Microbiol Biotechnol. 1995 Dec;44(3-4):439-43. doi: 10.1007/BF00169941.
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Regulated expression of the nor-1 and ver-1 genes associated with aflatoxin biosynthesis.与黄曲霉毒素生物合成相关的nor-1和ver-1基因的调控表达。
Appl Environ Microbiol. 1993 May;59(5):1642-6. doi: 10.1128/aem.59.5.1642-1646.1993.
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Cloning and characterization of a cDNA from Aspergillus parasiticus encoding an O-methyltransferase involved in aflatoxin biosynthesis.寄生曲霉中一个编码参与黄曲霉毒素生物合成的O-甲基转移酶的cDNA的克隆与特性分析
Appl Environ Microbiol. 1993 Nov;59(11):3564-71. doi: 10.1128/aem.59.11.3564-3571.1993.
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Cloning of the Aspergillus parasiticus apa-2 gene associated with the regulation of aflatoxin biosynthesis.寄生曲霉中与黄曲霉毒素生物合成调控相关的apa-2基因的克隆
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7
Molecular characterization of aflR, a regulatory locus for aflatoxin biosynthesis.黄曲霉毒素生物合成调控位点aflR的分子特征分析
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8
Variability among atoxigenic Aspergillus flavus strains in ability to prevent aflatoxin contamination and production of aflatoxin biosynthetic pathway enzymes.产毒黄曲霉菌株在预防黄曲霉毒素污染能力及黄曲霉毒素生物合成途径酶产生方面的变异性。
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Sequence variability in homologs of the aflatoxin pathway gene aflR distinguishes species in Aspergillus section Flavi.黄曲霉毒素途径基因aflR同源物的序列变异性可区分黄曲霉属Flavi组中的物种。
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Increased expression of Aspergillus parasiticus aflR, encoding a sequence-specific DNA-binding protein, relieves nitrate inhibition of aflatoxin biosynthesis.编码一种序列特异性DNA结合蛋白的寄生曲霉aflR表达增加，可缓解硝酸盐对黄曲霉毒素生物合成的抑制作用。
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