Mendenhall W M
Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USA.
Semin Radiat Oncol. 1998 Oct;8(4):262-9. doi: 10.1016/s1053-4296(98)80024-6.
This article reviews the results of radiation therapy alone for T3-4 squamous cell carcinoma of the larynx. Local control after radiation therapy is approximately 65% for patients with T3 glottic and supraglottic carcinoma. The likelihood of local control is inversely related to tumor volume and, for those with glottic cancers, is adversely influenced by cartilage sclerosis on pretreatment computed tomography of the larynx. Local control after radiotherapy is approximately 60% for T4 glottic cancers and 50% for T4 supraglottic carcinomas. The probability of severe complications is related to primary site and T-stage.
本文综述了单纯放射治疗喉T3-4期鳞状细胞癌的结果。对于T3期声门型和声门上型癌患者，放射治疗后的局部控制率约为65%。局部控制的可能性与肿瘤体积呈负相关，对于声门型癌患者，喉部治疗前计算机断层扫描显示的软骨硬化会对局部控制产生不利影响。T4期声门型癌放射治疗后的局部控制率约为60%，T4期声门上型癌为50%。严重并发症的发生率与原发部位和T分期有关。
