Emtestam L, Nicander I, Stenström M, Ollmar S
Department of Dermatology and Venereology, Huddinge University Hospital, Huddinge, Sweden.
Dermatology. 1998;197(4):313-6. doi: 10.1159/000018023.
Previously, we have explored the use of measurements of electrical impedance and devised 4 physically distinct indices named magnitude index (MIX), phase index, real part index and imaginary part index (IMIX) from the impedance data. Our results indicated that these indices could characterize contact reactions.
The goal of the present study was to use the electrical impedance method for the preoperative assessment of nodular basal cell carcinoma (BCC).
We included 11 patients with a total of 12 nodular BCC, diagnosed clinically and histologically. The noninvasive measurements were performed by transepidermal water loss (TEWL) and electrical impedance. For reference, normal looking contralateral or ipsilateral skin was used.
Compared to controls, the mean TEWL of BCC was increased, but this finding was not statistically significant. The electrical impedance measurements of BCC tissue revealed statistically significant changes of the impedance indices MIX and IMIX (p </=0.001).
The results suggest that the measurement of electrical impedance might become useful for investigations of BCC.
此前，我们探索了电阻抗测量方法，并根据阻抗数据设计了4个物理特性不同的指标，即幅值指数（MIX）、相位指数、实部指数和虚部指数（IMIX）。我们的结果表明，这些指标可以表征接触反应。
本研究的目的是使用电阻抗方法对结节性基底细胞癌（BCC）进行术前评估。
我们纳入了11例患者，共12个结节性BCC，均经临床和组织学诊断。采用经表皮水分流失（TEWL）和电阻抗进行无创测量。作为对照，使用外观正常的对侧或同侧皮肤。
与对照组相比，BCC的平均TEWL有所升高，但这一发现无统计学意义。BCC组织的电阻抗测量显示，阻抗指数MIX和IMIX有统计学意义的变化（p≤0.001）。
结果表明，电阻抗测量可能对BCC的研究有用。
