Gegnas L D, Waddell S T, Chabin R M, Reddy S, Wong K K
Department of Medicinal Chemistry, Merck Research Laboratories, Rahway, NJ 07065, USA.
Bioorg Med Chem Lett. 1998 Jul 7;8(13):1643-8. doi: 10.1016/s0960-894x(98)00285-6.
A series of transition-state analog inhibitors of the D-glutamic acid-adding enzyme (MurD) of bacterial peptidoglycan biosynthesis has been synthesized and evaluated for inhibition of the E. coli enzyme.
已合成了一系列细菌肽聚糖生物合成中D-谷氨酸添加酶（MurD）的过渡态类似物抑制剂，并对其抑制大肠杆菌该酶的能力进行了评估。
