Ding Y, Fukuda M, Hindsgaul O
Burnham Institute, La Jolla Cancer Research Center, CA 92037, USA.
Bioorg Med Chem Lett. 1998 Jul 21;8(14):1903-8. doi: 10.1016/s0960-894x(98)00332-1.
LacNAc-based oligosaccharides, including sialyl-(2-->3)-LacNAc, dimeric sialyl-(2-->3)-LacNAc, trimeric sialyl-(2-->3)-LacNAc, beta-glucuronyl-(1-->3)-LacNAc, and 3-sulfo-beta-glucuronyl-(1-->3)-LacNAc, were synthesized efficiently from a single protected LacNAc derivative having both OH-3' and 4' unprotected.
基于乳糖胺的寡糖，包括唾液酸基-(2→3)-乳糖胺、二聚唾液酸基-(2→3)-乳糖胺、三聚唾液酸基-(2→3)-乳糖胺、β-葡糖醛酸基-(1→3)-乳糖胺和3-磺基-β-葡糖醛酸基-(1→3)-乳糖胺，由一种同时使3'和4'位羟基未受保护的单一保护乳糖胺衍生物高效合成。
